Computed Tomographic Morphometry of Proximal Femur in Malay Population ab 49 EURO A cross sectional study in Advanced Medical & Dental Institute and Universiti Sains Malaysia Hospital
The relationship between Bone mineral density (BMD) and atherosclerosis in older postmenopausal women is a subject of increasing concern because of the great importance of atherosclerotic diseases in later life and the need to identify its potentially modifiable risk factors. This thesis was carried on 150 ambulant postmenopausal women apparently healthy (aging from 55 years old and above) in Ain Shams University Hospitals, Cairo, Egypt. Measurement of BMD of lumbar spine and femur neck by DEXA scan and measurement of intima-media thickness of both common and internal carotid arteries by ultrasonography with assessment of plaques and the degree of stenosis (if present) were carried out. The results of this study revealed that there is a statistically significant positive relation between the presence of plaques in carotid arteries and low BMD of both lumbar spine and femur neck. Multinomial logistic regression analysis showed that after controlling for age and duration of menopause, osteoporosis of femur neck could be used as a predictor for atherosclerotic plaques in postmenopausal women.
The humerus has rarely been tapped as a site for sex determination, though it has often demonstrated an even greater accuracy than other long bones such as the femur. Determination of sex is of medico legal importance and also useful to establish the identity in archaeological explorations. It is an attempt to connect to the peace of information in human evolution. Almost all bones of the human skeleton show some degree of sexual dimorphism. It is recognized that long bone cross-sectional area is greater in males compared to females, which is tough to reflect more rapid periosteal bone growth in boys. In the present study we were collected 100 dry human humeri of unknown sex from different medical institutions and Anthropology department of S.V University, Tirupati.Each humerus was measured for 14 parameters by using Osteometric board and sliding caliper and recorded the values. In the previous studies authors did not analyze possible differences among population related to relationship between total humeral length and the measurements of their segments. The present study reveals that humeri of unknown gender can be sexed to the extent of 75-80% by using above mentioned parameters.
The current study described in details the process of bone development (Endochondral ossification) in the femur and tibia of Japanese quail during different stages of pre-hatching and post-hatching development. The study carefully investigated the most dramatic morphological changes during the growth of quail in a wide range of developmental stages starting from 5 days of post-fertilization, when the first leg bud was seen until 45 days of post-hatching, when the long bone was completely formed. The results in this book are unique and are considered a very important baseline for the understanding the theory of the long bone growth in quail and subsequently a better understanding orthopedic diseases affecting birds used for meat production. This work was from the PhD thesis of Ms. Soha A. Soliman, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt 2011-2013 and Supervised by Dr. Yasser A. Ahmed (Lectuerer of Histology), Prof. Gamal Kamel (Prof. Of Histology) and Prof. Salma Mohamed (Prof. of Anatomy) and Edited primarily by Prof. Mohamed Nabil Kamel (Prof. of Histology).
The study investigated, comparatively the effects of plant extracts such as, garlic, ginger and onion on some organs (liver, kidney and heart), x-ray exposed rats, using and assaying for some biochemical enzymes. Twenty albino rats with average weight of (155.00 ± 2.01g), divided into five groups were used for the study. The rats with exception of the control were exposed to x-ray with ionizing radiation at a rate of 525kv/sec. The results indicated, some toxicity conferred on the rats were reversed when fed diet containing garlic, ginger and onion, evidently shown in some of the biochemical parameters examined that includes: body weight gain, plasma and femur alanine aminotransferase (ALP) activity, enzymatic changes in super oxide dismutase (SOD), catalase (CAT) level in the liver, kidney and heart. Feeding ginger, garlic and onions extracts failed to restore the x-ray induced inhibition of aldenylate oxidase (AO) and sulphite oxidase (SO) activities in the liver and heart. Data of the study indicated that garlic and onions had more beneficial effects on radiation induced toxicity in rats at least.
Anthropometry provides scientific methods and techniques for taking various measurements and observation on the living being and the skeleton.Stature is one of the numerous data for identification.The stature prediction occupies relatively a central position in the identification necessitated by the medicolegal experts or medical jurisprudence and also in the anthropological research.This study was taken up with the aim of finding out whether there is any correlation between stature & finger length,and also to find out which finger is best to estimate the stature of an individual, in males and females individually. Till date, most of the workers on stature estimation have used the length of long bones such as femur, tibia, humerus, radius, etc. A meagre data is available on previous works done for calculation of height from finger length. Hence an attempt is made to fill this lacuna. In the present study it was found that there is a significant correlation between stature and finger length. Ring finger is best to estimate stature in both males and females.
Bisoprolol fumarate (BF) is a synthetic _1- cardio selective adrenoreceptorblocking agent. BF can only used in treatment of cardiovascular disease such as (Hypertension and Myocardial Infarction). This is experimental study to bone showed the local effect of beta -1 selective blocker Bisoprolol fumarate gel 1% (BFG1%) on bone healing . The aims of this study were to demonstrate the physicochemical properties of BFG1% as well as identify the effect of this preparation on bone healing in rabbits through measuring certain biochemical parameters histological in addition to histomorphometric examination of the induced defect on rabbit's femur.
We had performed an anatomic study of the proximal femur morphometry based on measurements in 280 computed tomographic scanogram of the proximal femora. The following parameters were studied: femoral head diameter, vertical offset, horizontal offset and neck shaft angle. Overall, females were found to have significantly smaller dimensions in most of the parameters measured compared to males (p 0.3, p0.001). These positive correlations has a strong predictive value for determination of femoral head diameter, vertical offset and horizontal offset based on patient s height. The current study have shown that the proximal femur morphometry of Malay population was smaller compared to Caucasion and Thai population. However, some of the current available implant dimensions are bigger than the dimensions of the proximal femur in Malay population. Therefore, changes in implant design are required to optimize and restore the normal biomechanics of the hip joint in the Malay population.
The finite element method, one of the most advanced simulation techniques in solid mechanics, is used for orthopedic biomechanics. It is used as a tool for the design and analysis of total joint replacement and other orthopedic devices. The design of hip joint prostheses is a complex process that requires close co-operation between engineers and surgeons. One of the most important factors in the implant design is to reduce stress on the femur and the bone-cement. The purpose of this study is to investigate the behavior of newly designed implants under body weight load during stumbling by parametric modeling. In the parametric design, the prosthesis functional requirement is that the locking of stem to the femur head using cement should be strong enough to preclude unlocking during the life time of a patient and to prevent sliding of the implant into the bone-cement. These parameters are then optimized. Using the results of this investigation, the probability of failure was investigated for both the initial and shape-optimized prosthesis designs using several simple performance functions describing fatigue theory.